OUR SOLUTIONS

EVOrgansense™

Enhance Your EV Research with the Tool for Predicting the Impact of EVs on Organs and Cell Types

PROBLEM

Current extracellular vesicle (EV) and microRNA (miRNA)-based therapies lack predictive tools to determine where and how these molecules act in the body. Identifying which organs or cell types are most affected by EVs or miRNA regulatory network is slow, costly, and depends heavily on in vivo studies. Drug developers face major challenges in comparing EV sources for best therapeutic choice, optimizing their delivery, minimizing off-target effects, and gaining actionable insights into how to engineer EVs with specific miRNA regulatory network for targeted therapeutic impact.

OUR SOLUTION

EVOrgansense™ is a cutting-edge proprietary technology designed to map the impact of EVs and miRNA regulatory network on organs and cell types. It enables precise ranking of organs as well as cell types, from most to least affected, providing unparalleled insight into the functional effects of EVs when administered into the body. Beyond host organ and cell type impact assessment, EVOrgansense™ guides the strategic engineering of miRNA regulatory network within EVs to enhance their functional impact on your organs or cell types of choice while minimizing off-target and secondary effects on others. By offering a data-driven approach to EV and miRNA impact assessment, EVOrgansense™ revolutionizes the field, making precision therapeutics more accessible and effective—even before conducting in vivo studies. This enables streamlined workflows, reduced costs, and enhanced accuracy, accelerating the development of targeted and safer therapies.

Are you interested in any of the following?

  • Assessing which organs or cell types are most impacted by your EVs
  • Comparing different EV sources to choose the best option for your therapeutic goals
  • Engineering EVs with optimal miRNA regulatory networks to target specific organs, cell types, or pathways

What we need from you ?

  • Isolated EVs (we can perform miRNA sequencing and analysis) OR
  • Small RNA-seq data you’ve already generated (raw or processed) OR
  • A list of miRNAs (from EVs or cellular sources)

What we will deliver ?

  • Ranked organ or cell-type impact, including specific cell types within organs
  • Publication-ready figures and visualizations
  • Functional interpretation and pathway analysis to guide miRNA engineering for targeted therapeutic effects